I loved Dr. Horrible's Sing Along Blog. If you did too then you'll love this book. It doesn't make a lot of sense if you aren't familiar with Dr. Horrible. The stories in this graphic novel are really snippets of stories of the various characters. There's little character development because it was written with the idea that you already know the characters.
If you haven't seen Dr. Horrible's Sing Along Blog, definitely do a youtube search and watch it (we found the complete "movie" at our library on DVD). It is a musical and it is a comedy. It's all good fun where you'll be rooting for the bad guy to win.